The Tissue Transglutaminase IgA (tTG-IgA) Test detects antibodies produced in response to gluten in individuals with celiac disease, an autoimmune disorder affecting the digestive system. In celiac disease, the immune system mistakenly targets gluten as harmful, causing inflammation and damage to the small intestine. This test helps diagnose celiac disease and monitor its progression or response to a gluten-free diet.

Positive Result: Indicates the presence of celiac disease; further evaluation with a biopsy may be required. Negative Result: Suggests the absence of celiac disease but does not rule out other forms of gluten sensitivity. Conditions Monitored: Celiac disease Gluten intolerance Nutrient malabsorption

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