The Double Marker Test is a first-trimester screening test performed during pregnancy to assess the risk of chromosomal abnormalities in the fetus, such as Down Syndrome (Trisomy 21) and Edward’s Syndrome (Trisomy 18). This test evaluates two markers in the blood: Free Beta-HCG: A hormone produced during pregnancy. PAPP-A (Pregnancy-Associated Plasma Protein-A): A protein associated with fetal development. This predictive test does not confirm abnormalities but provides risk levels, enabling early intervention if needed.

Normal Results: Low risk of chromosomal abnormalities; pregnancy progresses normally. Abnormal Results: Elevated risk of neurological or chromosomal abnormalities; further diagnostic tests like amniocentesis may be recommended. Conditions Monitored: Down Syndrome (Trisomy 21) Edward’s Syndrome (Trisomy 18) Neurological abnormalities The test is especially crucial for pregnant women aged 35 years or older due to increased risk of chromosomal disorders in the fetus.

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